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The status of Peste des Petits Ruminants (PPR) in Rwanda is unknown, despite its prevalence in neighboring countries. A cross-sectional sampling of goats and sheep was carried out in five districts of Rwanda located closer to neighboring countries endemic to PPR. Serum samples were analyzed using a commercial ELISA, to detect antibodies to PPR virus (PPRV). Sixty-eight samples [14.8, 95% Confidence Interval (CI) 11.7-18.4] were seropositive for PPR, of which 17.4% (95% CI 11.6-24.6; 25/144) were from sheep, whereas 13.6% (95% CI 10.0-17.