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Consequently, SSB1 (30 mg/kg, ip) and SSD (10 mg/kg, ip) displayed excellent in vivo inhibitory activity in MB allografts, and the tumor growth inhibition ratios were approximately 50% and 70%, respectively. Our findings, thus, identify SSB1 and SSD significantly inhibit tumor growth in MB models by inhibiting the Hedgehog pathway through targeting SMO.Phytoproducts are involved in various fields of industry. Small-molecule (Mw less then 900 Da) organic compounds can be used to indicate the quality of plant samples in the perspective o
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