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The pressure-controlled CT-protocol combines a complete lung ability scan (TLC PC-CT) with a near functional recurring capacity scan (FRC PC-CT) under basic anesthesia, while another CT-protocol is obtained during free breathing (FB-CT) near useful residual capability. The purpose of this research was to assess the sensitiveness in finding airways disease of both protocols in two cohorts. METHODS Routine PC-CTs (Princess Margaret kids' medical center) and FB-CTs (Erasmus MC-Sophia kids me