https://www.selleckchem.com/pr....oducts/cariprazine-r
05). In addition, lesions from TRAM-34 treated mice contained less collagen (6% ± 1% vs. 15% ± 2%; p less then 0.05), fibronectin (14% ± 3% vs. 32% ± 3%; p less then 0.05) and smooth muscle content (19% ± 2% vs. 29% ± 3%; p less then 0.05). Conversely, TRAM-34 had no effect on total cholesterol (1455 vs. 1334 mg/dl, PO and TRAM, resp.) or body weight (29.1 vs. 28.8 g, PO and TRAM, resp.). Medial smooth muscle of atherosclerotic carotids showed diminished RE1-Silencing Transcription Factor (REST)/Neural Restrictive Silencing
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