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https://www.selleckchem.com/pr....oducts/zanubrutini-b
Inorganic orthophosphate (Pi) is an essential nutrient for plant growth and its availability strongly impacts crop yield. PHOSPHATE1 (PHO1) transfers Pi from root to shoot via Pi export into root xylem vessels. In this work, we demonstrate that an upstream open reading frame (uORF) present in the 5' UTR of the Arabidopsis thaliana PHO1 inhibits its translation and influences Pi homeostasis. The presence of the uORF strongly inhibited the translation of a PHO1 5'UTR-luciferase construct in protoplasts. A point mutation remov