https://www.selleckchem.com/pr....oducts/Gefitinib.htm
To study the expression of Shh singaling related gene, including Shh, Ptch1, Smo and Gli1 in bone marrow CD34 cells of patients with myelodysplastic syndrome(MDS) and acute myeloid leukemia with myelodysplasia-related changes(AML-MRC), and to explore their clinical significance. The count of CD34 cells in bone marrow was detected by flow cytometry in 53 patients with MDS and 30 patients with AML-MRC. Magnetic beads were used to separate CD34 cells. The expression of Shh, Ptch1,Smo and Gli1 on CD34 cells was detected by qRT-PCR, the ef
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