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NEW FINDINGS What is the topic of this review? This review focuses on the elevated demand placed on the respiratory muscle during whole-body exercise induced hyperpnoea, its role in the neural modulation of cardiovascular control; at the level of both respiratory and locomotor skeletal muscle and considers the mechanisms responsible. What advances does it highlight? Recent evidence suggests there a sympathetic restraint of blood flow to locomotor muscles during near maximal exercise, the purpose may be to maintain blood pressure. It also
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