https://www.selleckchem.com/pr....oducts/17-AAG(Geldan
SHR-SO. The MR was associated with increased cardiomyocyte expression of CaN/NFAT and β-catenin along with its intracellular re-distribution. TRPC6 protein levels were substantially elevated in both SHR groups with higher mRNA expression in SHR-NE. The Wnt/β-catenin and TRPC6/CaN/NFAT hypertrophic signaling pathways seem to be involved in myocardial remodeling in the settings of AH and CKD and might be mediated by FGF23 and α-Klotho axis. The Wnt/β-catenin and TRPC6/CaN/NFAT hypertrophic signaling pathways seem to be involv
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