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The protein-protein discussion showed the useful association of the source genes (CTNNB1, NNMT, PTCH1, CALD1, CXCL14, CXCL8, and TNFAIP3) with the target proteins, such as AXIN, MAPK, IL6, STAT, APC, GSK3B, and SHH. Conclusion The integrated pathway analysis suggested the role of the genes in important physiological answers, such as for instance mobile period regulation, WNT, hedgehog, MAPK, and calcium signaling pathways during colorectal cancer. These pathw