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https://www.selleckchem.com/pr....oducts/pf-06882961.h
0 years-68.0 years]) with a median follow up of 2.5 years (1.07 years-3.56 years). The iECV significantly increased with AR severity (P0.001), whereas ECV and replacement fibrosis did not (P = NS). On multivariate analysis, iECV remained associated with the composite event (P = 0.01). On Kaplan-Meier analysis stratified by AR regurgitant fraction (RF) and iECV, patients with AR RF severity≥30% and iECV≥24mL/m demonstrated the highest event rate. Among CMR biomarkers of fibrosis, iECV was more closely associated than replacement