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ierarchical model. This approach gained statistical power for the dichotomized endpoints by leveraging the information in the continuous data. Furthermore, the Bayesian analysis enabled additional insights into data interpretation and inference by providing posterior distributions for parameters of interest and posterior probabilities of different hypotheses that were not available with the frequentist approach. ClinicalTrials.gov Identifier NCT02456636 ; date of registry May 28, 2015. ClinicalTrials.gov Identifier NCT02456636 ; date