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Many self-propelled objects are large enough to exhibit inertial effects but still suffer from environmental fluctuations. The corresponding basic equations of motion are governed by active Langevin dynamics, which involve inertia, friction, and stochastic noise for both the translational and orientational degrees of freedom coupled via the self-propulsion along the particle orientation. In this paper, we generalize the active Langevin model to time-dependent parameters and explicitly discuss the effect of time-dependent inertia for ach