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DETR correctly localized 80% of the lesions, and it achieved a specificity of 81% (95% CI 67, 91) and a sensitivity of 82% (95% CI 62, 10 for FLL characterization (benign vs malignant) among lesions localized by all raters. The performance of DETR met or exceeded that of two experts and Faster R-CNN for these tasks. DETR demonstrated high specificity for detection, localization, and characterization of FLLs on abdominal US images. RSNA, 2022 Computer-aided Diagnosis (CAD), Ultrasound, Abdomen/GI, Liver, Tissue Characterization, Superv