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d even minor LLD in the setting of THA. To describe out-of-hospital ketamine use, patient outcomes, and the potential contribution of ketamine to patient death. We retrospectively evaluated consecutive occurrences of out-of-hospital ketamine administration from January 1, 2019 to December 31, 2019 reported to the national ESO Data Collaborative (Austin, TX), a consortium of 1,322 emergency medical service agencies distributed throughout the United States. We descriptively assessed indications for ketamine administration, dosing, route, t