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Their average onset age of seizures had been around 2 months, and all of them have intractable epileptic seizures, extreme intellectual impairment, and hypotension. Among them, two provided infantile spasm and high arrhythmia in EEG, and the other manifested clonic seizure and wide epileptiform discharge in EEG. Extracerebral room widening in cranial MRIs was demonstrated in two cases. Artistic evoked potential had been abnormal in 2 cases. Seizures had been resistant t