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Neutropenia can occur from untreated autoimmune hyperthyroidism (AIH) or methimazole (MMI); starting MMI in children and adolescents with AIH and neutropenia could thus be worrisome. We aimed to describe the prevalence of neutropenia in children and adolescents with AIH prior to treatment with antithyroid drugs and to assess the effect of antithyroid drugs on the neutrophil count. This was a retrospective study of patients with AIH seen at a Pediatric Endocrinology clinic. ANC data at presentation and during anti-thyroid