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A two-dimensional model MIKE21 coupled with a modified EcoLab module was applied to model the water quality of surface flow wetlands. In the model, vegetation effects, oxygen production, nutrient consumption by microorganisms and vegetation were set in the solutions of hydrodynamic, chemical, and biological processes. Based on the field investigation and measurements in the Guishui River wetland, the model was established for the downstream reaches of the Guishui River and the Sanli River. The model calculated the hydrodynamics and wate