https://www.selleckchem.com/pr....oducts/bgj398-nvp-bg
Brain-derived neurotrophic factor (BDNF) and its receptor tyrosine receptor kinase B (Trk have been shown to play an important role in numerous neurological disorders, such as Alzheimer's disease. The identification of biologically active compounds interacting with TrkB serves as a drug discovery strategy to identify drug leads for neurological disorders. Here, we report effective immobilization of functional TrkB on magnetic iron oxide nanoclusters, where TrkB receptors behave as "smart baits" to bind compounds from mixture
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