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https://www.selleckchem.com/GSK-3.html
Amongst 157 participants with longer follow-up (≥60 days), PASC prevalence was 77.1%.Modeling the impact of amino acid mutations on protein-protein interaction plays a crucial role in protein engineering and drug design. In this study, we develop GeoPPI, a novel structure-based deep-learning framework to predict the change of binding affinity upon mutations. Based on the three-dimensional structure of a protein, GeoPPI first learns a geometric representation that encodes topology features of the protein structure via a self-supervised learning sch