https://gsk5959inhibitor.com/p....rogram-rpe-breakpoin
Integrin αvβ3 abundantly expresses on osteoclast and plays a critical part into the development and function of osteoclast, therefore, blockage of αvβ3 has grown to become an attractive therapeutic option for osteolytic conditions. In this research, we find that Tablysin-15, a RGD motif containing disintegrin, concentration-dependently suppresses RANKL-induced osteoclastogenesis, F-actin ring development and bone resorption without affecting the cellular viabilities. Tablysin-15 b
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