https://www.selleckchem.com/pr....oducts/danicopan.htm
The most abundant reactions were ester hydrolysis, ester hydrolysis combined with glucuronidation, and ester hydrolysis combined with hydroxylation at the tert-butyl moiety. The parent compound was only found up to one hour after administration in pig urine. The metabolite formed after hydroxylation and glucuronidation was detectable for 2 h, the one formed after ester hydrolyzation and defluorination for 4 h after administration. All other metabolites were detected during the whole sampling time. The most abundant metabolites were al
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