https://www.selleckchem.com/pr....oducts/zidesamtinib.
Results Cross-sectional comparisons revealed significantly increased grooming parameters in ko animals, at both time points. A significant longitudinal increase in % grooming duration (+268.25%; p less then 0.05) reflected aggravation of this behavior in ko mice. [11C]ABP688 μPET revealed significantly lower mGluR5 availability in the cortex, striatum, hippocampus, and amygdala of ko mice at both ages. A significant longitudinal BPND decline was present for ko mice (p less then 0.01 cortex -17.14%, striatum -19.82%, amygdala -23.57