https://www.selleckchem.com/pr....oducts/shin1-rz-2994
In the TCGA cohort, high CD68 mRNA levels were associated with better outcome (p = 0.02). Macrophages enhanced FOLFOX cytotoxicity on CRC cells (p less then 0.01), and drugs oriented macrophage polarization from M2- to M1-phenotype. Low TAM densities identify stage III CRC patients at higher risk of recurrence after adjuvant therapy, and macrophages can augment the chemo-sensitivity of micro-metastases.The purpose of this study was to compare the reconstructive outcomes of soft-tissue defects around the foot and ankle with antero