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We discovered that the development of hypertension occurred quicker in previously PE rats than in regular pets. VEGF, PEDF, (P)RR and AT1R were increased in PE, however in L-NAME-induced hypertension only (P)RR and AT1R were modified. Eye fundal information suggested that PE caused a level I retinopathy, but L-NAME induced a faster and more severe retinopathy in formerly PE animals in comparison to previously typical pregnancy rats. These results indicate that PE predis
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