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After creating a targeted deletion mutant in usp, we had been able to concur that usp notably plays a part in success in PBS and this defect was restored by in trans complementation. The usp gene is present in 99% of a collection of 1644 E. faecium genomes that collectively span the variety regarding the species. We postulate that usp is a key determinant for the remarkable ecological robustness of E. faecium. Further mechanistic researches into usp along with other genetics identified in this st
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