https://www.selleckchem.com/pr....oducts/1-deoxynojiri
Inhibition of HIF-1α activity dampened liver fibrosis in mice. Similarly, pharmaceutical inhibition of TWIST alleviated liver fibrosis in mice. In conclusion, our data suggest that epigenetic activation of TWIST by BRG1 contributes to the modulation of endothelial phenotype and liver fibrosis. Therefore, targeting the HIF1α-BRG1-TWIST axis may yield novel therapeutic solutions to treat liver fibrosis.MicroRNAs (miRNAs) are a major class of conserved non-coding RNAs that have a wide range of functions during development and di
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