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Whole brain radiation (WBRT) may lead to acute xerostomia and dry eye from incidental parotid and lacrimal exposure, respectively. We performed a prospective observational study to assess the incidence/severity of this toxicity. We herein perform a secondary analysis relating parotid and lacrimal dosimetric parameters to normal tissue complication probability (NTCP) rates and associated models. Patients received WBRT to 25-40Gy in 10-20 fractions using 3D-conformal radiation therapy without prospective delineation of the parotids or lac
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