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This review provides a brief on lipid based drug delivery nanocarrier and the mechanisms by which lipids and lipidic excipients improve the oral absorption of drugs with poor aqueous solubility and also provides a viewpoint on the promising applications of lipidic nanoparticulate systems. Copyright© Bentham Science Publishers; For any queries, please email at epub@benthamscience.net.Heterocyclic compounds hold a huge and recognized place in the field of medicinal chemistry thanks to their multiple biological activities. Their synthetic