https://www.selleckchem.com/pr....oducts/bay-2402234.h
RESULTS In total, 10 SNPs around the propeller domain were identified; one synonymous SNP and nine non-synonymous SNPs, and two insertions. Three of these SNPs (T478T, A578S and V637I) were located in the propeller domain. A578S, is the most frequent mutation observed in Africa, but has not previously been reported in Senegal. A previous study has suggested that A578S could disrupt the function of the Pfk13 propeller region. CONCLUSION As the genetic basis of possible artemisinin resistance may be distinct in Africa and Southeast As
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