https://www.selleckchem.com/
BACKGROUND Diffusely abnormal white matter (DAWM) regions are observed in magnetic resonance images of secondary progressive multiple sclerosis (SPMS) patients. However, their role in clinical progression is still not established. OBJECTIVES To characterize the longitudinal volumetric and intensity evolution of DAWM and focal white matter lesions (FWML) and assess their associations with clinical outcomes and progression in SPMS. METHODS Data include 589 SPMS participants followed up for 3 years (3951 time points). FWML and DAWM were automatically segmented
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