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For oxidative stress analysis, the peripheral blood mononuclear cells were separated and mitochondrial superoxide anion manufacturing was calculated making use of MitoSOX Red test. Pills adherence ended up being evaluated predicated on Morisky-Green and MedTake tests. Well being evaluation was done using EORTC QLQ C-30 and QLQ HCC18 surveys. The results showed that hand-foot problem (45.5%), thrombocytopenia (45.5%), diarrhea (54.5%), discomfort (54.5%), and exhaustion (36.4%) had been th