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72%) on DTG, 1/1,497 (0.07%, 95% CI 0.00%, 0.37%) on EFV. MTCT was similar for women starting each ART regimen in pregnancy 8/999 (0.80%, 95% CI 0.35%, 1.57%) for DTG and 8/883 (0.91%, 95% CI 0.39%, 1.78%) for EFV (risk difference 0.11%, 95% CI -0.79%, 1.06%). Most MTCT events (4/8 with DTG, 6/9 with EFV) occurred when ART was started less then 90 days before delivery. Infants exposed to DTG in utero had lower baseline HIV RNA compared with other HIV-infected infants. CONCLUSION In utero MTCT in Botswana remains rare in the DTG era. No