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Challenges of ADHD in Women and Girls Girls and women often face many challenges when untreated ADHD symptoms impact their lives. They may feel inadequate at work, struggle with peer relationships, and suffer from anxiety or depression. They also have a better chance of developing strategies to manage their ADHD symptoms. This makes it more difficult to identify and treat them. Symptoms Although research shows that ADHD affects boys and men more frequently than girls and women, the gender gap narrows