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Earlier research reports have identified the imbalance between extracellular matrix (ECM) catabolism and anabolism in cartilage structure given that primary cause. Up to now, there's absolutely no cure for OA despite several symptomatic treatments. This research aimed to research the part of CircCDK14, a novel circRNA aspect, in the progression of OA, and to elucidate its underlying molecular mechanisms. Techniques the event of CircCDK14 in OA, plus the relationship between CircCDK14 and