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In this context, the 1,3,4-oxadiazole motif may be a valuable device worth developing for the procurement of novel and potent selective CAIs potentially useful for the management of many different diseases as chemotherapeutic agents. Microsomal epoxide hydrolase (mEH) hydrolyzes many epoxide containing molecules. Although mixed up in metabolism of xenobiotics, present researches associate mEH with all the onset and development of particular condition conditions. This event is partially attribute