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Thus, our data reveal a previously unrecognized role for microglia in CBF regulation, with broad implications for common neurological diseases.Atkins et al. (2022. J. Exp. Med.https//doi.org/10.1084/jem.20211924) create a PSC differentiation model for human yolk sac hematopoiesis and discover multipotent progenitors with erythro-myeloid and T lymphoid potential. The multipotent progenitors emerge via hemogenic endothelium and share origin with primitive erythroid wave in KDR+CD235a/b+ mesoderm.β-Secretase 1 (β-site amyloid precursor prot
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