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This suggests that cyprinivirus species may have undergone much more vigorous purifying selection post species clade divergence. We discuss whether this may be linked to biological and anthropogenic factors or to sampling bias, and we propose that the comparison of short-term evolutionary rates between species may provide further insights into these differences.The tumor microenvironment plays a critical role in the control of metastasis. The epithelial-mesenchymal transition (EMT) is strongly associated with tumor metastasis, and cons
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