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The evidence from human research about the role of milk thistle in oral diseases is limited. Further studies, particularly clinical trials, to test milk thistle either as a potential treatment modality or a supplementary therapy for oral diseases on higher levels would be useful in the future. Milk thistle has antioxidant, anti-inflammatory, anticancer, antifungal, immunomodulatory, and other properties. The evidence from human research about the role of milk thistle in oral diseases is limited. Further studies, particularly clinical tr