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Citicoline is a drug used both in degenerative and in vascular cognitive decline; memantine is a drug used for the treatment of mild to moderate Alzheimer's disease (AD). Our hypothesis is that their combined use could have an enhanced action in patients affected with AD and mixed dementia (MD) too. We report the main tips from a recent study on the use of these drugs, the CITIMEM study. The study was retrospective and was performed on 126 patients aged 65 years old or older affected with AD or MD (mean age 80.7 ± 5.2 years old) who had
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