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Under the conditions of this experiment, no significant effects were found on immune function of F3 SD rats through the three generation development study of genetically modified maize with CrylAb and epsps genes. In order to investigate the effect of yeast on reducing mycotoxin damage in dried fish. A strain of Meyerozyma guilliermondii MH 211588. 1(MG-81) was mixed and fermented 48 h with dried Lutjanus erythopterus which contaminated aflatoxin B_1(AFB_1) and T-2 toxin(T-2). The toxin concentration in fermentation at different time was