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001). Also, the ratios of the insular volume to total brain and cerebral volume were significantly higher in males than in females (p 0.05). This study shows that insular volume differs with laterality and gender. This outcome may be explained by the anatomical relationship between the insula and behavioural functions and emotional reactions and the fact that the right side of the brain is best at expressive and creative tasks. This study shows that insular volume differs with laterality and gender. This outcome may be explained by the