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Affected women with rs1501299 TT had somewhat reduced adiponectin and greater leptin than GT and GG genotypes. GT genotype was notably linked to the illness status [odds ratio (OR)=3.24, 95% confidence interval (95% CI)=1.03-10.17]. Women in the low tertile of serum adiponectin had a RR of BRCA-associated cancer of 2.80, 95% CI=1.1-7.1 (p for trend=0.03) compared with women in the higher tertile. SUMMARY within the SNP rs1501299 the T allele was substantially connected w