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This study suggests that the application of ionic gold as an alternative antimicrobial is promising, particularly against AMR P. aeruginosa. The antimicrobial activity of ionic gold against P. aeruginosa could potentially be utilised as an alternative therapeutic option in wound management, an approach that could benefit healthcare systems worldwide. The aim of this study was to establish a model to estimate the level of arterial oxygen saturation (SpO ) and help determine the appropriate hypoxic dose in humans exercising in acute hypox