https://www.selleckchem.com/pr....oducts/piperlongumin
Despite concern about harms related to long-term prescribed opioid use among individuals with chronic noncancer pain (CNCP), no study has examined whether the same patients engage in a risky pattern of use consistently for the long term. To examine the prevalence, incidence, persistence, and cessation of a range of opioid behaviors, indicators of extramedical use, and harm among individuals who are prescribed opioids. This 5-year prospective cohort study in communities across Australia included 1514 adults who were prescribed opi