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Exosomes can change the microenvironment, but the microenvironment can also change the composition of exosomes. Exosomes obtained from sick patients carry markers characteristic of the corresponding disease. Such exosomes can have pro-inflammatory, pro-fibrotic, cytotoxic, and oncogenic properties, and disrupt cellular cooperation. Until now, questions regarding the dose, reactions to repeated administration, and dosage regimes have not been completely resolved. Exosomes obtained from sick patients carry markers characteristic of the cor