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224; p=0.022) and ERBF (β=0.203; p=0.02 and a positive trend for hyperemia and mGFR (β=0.391; p=0.053) were observed, while a negative association for post-occlusive capillary density with ERVR (β=-0.196; p=0.027) was found. These findings indicate that microvascular dysfunction in overweight adults with T2D is associated with lower mGFR and ERPF and higher ERVR. We hypothesize that increased renal vascular resistance may contribute to glomerular dysfunction due to impaired renal perfusion. These findings indicate that microvascular d