https://www.selleckchem.com/pr....oducts/etomoxir-na-s
Modes of interactions of small ligands with CYP3A4 have been defined using the Template established in our previous studies (DMPK. 34 113-125 2019 and 34 351-364 2019). Interactions of polyaromatic hydrocarbons such as benzo[a]pyrene, pyrene and dibenzo[a,j]acridine were refined with the idea of Right-side movement of ligands at Rings A and B of Template. Expected formation of metabolites from the placements faithfully matched with experimentally observed sites of their metabolisms and also with preferred orders of regio-isomer
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