https://www.selleckchem.com/products/c381.html
Administration of miR-124 antagomir in hippocampus inhibited miR-124 expression in hippocampus of CUMS rats. Additionally, SPT, OFT, EPM, and FST also showed that miR-124 antagomir can reduce the depression-like behavior of CUMS rats. Furthermore, miR-124 antagomir injection increased the levels of NE, DA and 5-HT in the hypothalamus of CUMS rats. Moreover, miR-124 antagomir injection increased the expression of cyclic AMP-responsive element binding protein1 (CREB1) and brain-derived neurotrophic factor (BDNF) in hippocampus. Using a dual
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