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We intend to describe a case of McCune-Albright Syndrome (MAS), a rare disease characterized by fibrous dysplasia (FD), cutaneous hyperpigmentation and hyperfunctioning endocrinopathies (HFE). We report the case of a 13-year-old male child who presented with a macule in the lumbosacral region and disabling polyostotic FD, requiring several surgical interventions and bisphosphonates from the age of 3years (Y)+9months (M)due to persistent and severe pain. Hyperthyroidism (HT) became apparent at 5Y+1M with a T3/T4 ratio greater than 20. Trea
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