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This scientific commentary refers to 'Plasma total-tau, neurofilament light chain and amyloid-β levels and risk of dementia a population-based study' by de Wolf et al. (https//doi.org/10.1093/brain/awaa054), and 'Relationship of amyloid-b1-42 in blood and brain amyloid Ginkgo Evaluation of Memory Study' by Lopez et al. (https//doi.org/10.1093/braincomms/fcz038), two papers that illustrate these latest developments.Parkinson's disease is characterized by a gradual loss of dopaminergic neurons, which is associated with altered neuronal a
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